Infectious diseases resistant to treatment could become increasingly common and severe without a coordinated international effort to thwart them.
Medicines against microbes tend to become less effective over time. But a report from the Center for Global Development finds that resistance to the drugs is hastened in many countries by drug misuse, weak health systems and overuse of the medicines in agriculture.
Drug-resistant strains of major infectious diseases, such as malaria, pneumonia and tuberculosis have already emerged. And in some cases, drug-resistant mutations have become the dominant strain. Some examples:
The problem isn't restricted to poor countries. In the United States, the "superbug" methicillin-resistant Staphylococcus aureas (MRSA) went from accounting for 2 percent of hospital staph infections in 1974 to more than 50 percent in 2004.
The report also says that international donors' efforts to improve access to drugs in the developing has helped fuel drug resistance.
Work to curb the problem has mostly been disease- or country-specific, according to Rachel Nugent, CGD's deputy director for global health and chair of the group that prepared the report. “Some have been more successful than others, but none have addressed the problem on a global scale and across diseases," she says, adding that a "systemic global response" is missing.
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