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CBS' Two and a Half Men ends a 12-season run tonight as TV's longest-running multicamera sitcom. NPR TV Critic Eric Deggans says some experts still struggle to explain the show's longtime success.

Wilmore is still fine-tuning The Nightly Show, which fills the late-night spot on Comedy Central vacated by Stephen Colbert. The show launched just as Wilmore's 20-year marriage was coming to an end.

Prince Turki al-Faisal, the ex-Saudi intelligence chief, says the "pinprick" attacks against the Islamic State are not proving effective. He also says the campaign needs to be better coordinated.

The Food and Drug Administration has approved a drug that thwarts some enzymes breast cancer cells use to evade treatment with estrogen-blocking drugs.

The Pullman Historic District on Chicago's far south side was one the country's first company towns where workers at the now defunct Pullman Palace Car Company built luxury rail cars.

A company financially backed by the Retirement Systems of Alabama is on the hook for nearly all of a 14 million dollar lawsuit. Five Indian guest workers…

In a speech last week, FBI Director James Comey addressed racial tensions between police and minorities. A new effort in his hometown of Yonkers, N.Y., tries to get officers and young people talking.

The couple acted quickly on the judge's order, getting a license and having a ceremony, but the Texas attorney general said the marriage was void.

NPR's Susan Stamberg has talked to everyone from focus pullers to foley artists. She finds that in the last 10 years, technology and out-of-state tax incentives have been Hollywood game-changers.

Malaria parasites in Myanmar are learning how to fend off the incredibly effective drug called artemisinin. That could cause a lot of problems there — and beyond.