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A huge, expensive new development may temporarily displace the subterranean tavern, which has remained the same since 1964. John Belushi immortalized the place in a Saturday Night Live skit.

For decades, knowing your cholesterol number was the first step in preventing heart disease and stroke. Heart specialists would shift away from specific cholesterol targets under new guidelines. A risk-based approach tailored to each patient would become the new norm.

Twenty-nine lawmakers are supposed to come up with a long-term budget deal by mid-December. They meet again Wednesday around a conference table, facing huge hurdles and led by two people who couldn't be more different: Democratic Sen. Patty Murray of Washington state and Republican Rep. Paul Ryan of Wisconsin.

U.S. combat operations in Afghanistan are set to end after next year. So if the fighting stops, does the war on terror end? What does the end of the war mean for the detention center in Cuba and on drone strikes in Afghanistan?

The computer coders who made healthcare.gov may not have had the best of e-commerce in mind. The site looks like something melded together by a dozen government bureaucracies, and is so bad, it's driven away online shoppers. But a group of coders in Silicon Valley says it doesn't have to be this way. They've created healthsherpa.com.

The late artist's Three Studies of Lucian Freud is now the most expensive piece of art ever sold at auction. Also at Christie's, Andy Warhol's Coca-Cola (3) went for $57.3 million. Sculptor Jeff Koons' Balloon Dog (Orange) sold for $58.4 million, an auction record for a living artist's work.

It's midnight, and you're hungry. If picking up the phone or using an app is too much hassle, a new innovation has you covered. You could call it "the emergency pizza button."

The U.N.'s 2013 Afghanistan Opium Survey also said production in 2013 rose 49 percent over 2012 levels. The increased production comes as international troops prepare to withdraw from the country in 2014.

The first bite of a bitter fruit or nut can be shocking, even revolting. That's led scientists to think that bitter tastes evolved to help us avoid poisonous plants. But a new a genetic study in Africa challenges that notion.

As an aid worker, Jessica Alexander worked in Rwanda, Sudan, Sierra Leone, and Haiti, but don't call her a hero or a saint. Alexander tells Michel Martin about why she wanted to challenge perceptions of aid workers in her new book, Chasing Chaos: My Decade In and Out of Humanitarian Aid.