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Journals usually require researchers to reveal genetic sequences for a toxin that is the subject of a scientific paper. The requirement was waived for a new botulinum toxin because of security risks.

The Nobel Prize in Chemistry was awarded jointly to Martin Karplus, Michael Levitt and Arieh Warshel Wednesday. Karplus, Levitt and Warshel won the prize for laying the foundation for computer models that help researchers understand and predict chemical processes like the purification of exhaust fumes or photosynthesis in green leaves.

Are House Republicans still seeking Democratic concessions on the Affordable Care Act? Or have they switched their sights to even bigger targets: federal spending on entitlements like Medicare and Social Security?

Melissa Block talks to Sen. Susan Collins, (R-Maine) about her compromise plan to end the fiscal crisis.

For a view of the partial government shutdown across the country, Melissa Block talks to Felice Belman, opinion editor of the Concord Monitor in Concord, N.H.; Patrick Malone, political reporter for The Coloadoan based in Fort Collins, Colo.; and Brian Pearson, managing editor of the Tyler Morning Telegraph in Tyler, Texas.

As Congress looks for a way out of the current crisis, many Republicans are hoping for a big budget initiative to make worthwhile the pain of a government shut down and threatened debt default. Toward that end, House Budget Committee chairman and former GOP vice presidential nominee Paul Ryan floated a plan in Wednesday's Wall Street Journal. He makes the case for President Obama to negotiate with House Republicans on a deal to end the government shutdown and raise the debt ceiling. Ryan focused on the need to reform the tax code and make cuts to entitlement programs like Medicare, and cited a history of debt ceiling compromises between Republicans and Democrats.

Bill Minutaglio and Steven L. Davis have written a portrait of the city that saw John F. Kennedy's death firsthand. In those years, they say, Dallas was a roiling stew of superpatriotism and Communist paranoia — and, above all, distrust of the president.

The partial shutdown of the federal government is starting to take a bite out of the housing market, and would-be homeowners are feeling the impact in stalled mortgage approvals and delayed closings.

The government shutdown is starting to hamper trade. More than 40 federal agencies involved in trade shipments — from the EPA to the Commerce Department — have trimmed their staffs, resulting in a slowdown or halt of goods.

The genre has some of the most creative, politically savvy, intelligent female personalities in the industry.